PO-1026: LDR prostate brachytherapy inverse planning including dose-volume relation and tissue heterogeneity

Evaluation of the effect of prostate volume change on tumor control probability in LDR brachytherapy

PURPOSE This study evaluates low dose-rate brachytherapy (LDR) prostate plans to determine the biological effect of dose degradation due to prostate volume changes. MATERIAL AND METHODS In this study, 39 patients were evaluated. Pre-implant prostate volume was determined using ultrasound. These images were used with the treatment planning system (Nucletron Spot Pro 3.1(®)) to create treatment...

The use of nomograms in LDR-HDR prostate brachytherapy

PURPOSE The common use of nomograms in Low Dose Rate (LDR) permanent prostate brachytherapy (BT) allows to estimate the number of seeds required for an implant. Independent dosimetry verification is recommended for each clinical dosimetry in BT. Also, nomograms can be useful for dose calculation quality assurance and they could be adapted to High Dose Rate (HDR). This work sets nomograms for LD...

Brachytherapy dose‐volume histogram commissioning with multiple planning systems

The first quality assurance process for validating dose-volume histogram data involving brachytherapy procedures in radiation therapy is presented. The process is demonstrated using both low dose-rate and high dose-rate radionuclide sources. A rectangular cuboid was contoured in five commercially available brachytherapy treatment planning systems. A single radioactive source commissioned for QA...

Interstitial Brachytherapy (LDR-Brachytherapy) in the Treatment of Patients with Prostate Cancer

Objectives: As the number of patients with prostate cancer treated with permanent radioactive implants is increasing world wide, long-term data on tumor control and treatment morbidity become available. Materials: Biochemical and clinical tumor control appears to be as effective as after radical prostatectomy or external beam radiation therapy in early prostate cancer. Results: The risk of post...

Reporting in Brachytherapy: Dose and Volume Specification